Metabolites of Glutamate Metabolism Are Associated With Incident Cardiovascular Events in the PREDIMED PREvencion con DIeta MEDiterranea (PREDIMED) Trial [Epidemiology]
Conclusions
Baseline glutamate was associated with increased CVD risk, particularly stroke, and glutamine-to-glutamate ratio was associated with decreased risk. Participants with high glutamate levels may obtain greater benefits from the Mediterranean diet than those with low levels.
Clinical Trial Registration
URL: www.controlled-trials.com. Unique identifier: ISRCTN 35739639.
Source: JAHA:Journal of the American Heart Association - Category: Cardiology Authors: Zheng, Y., Hu, F. B., Ruiz-Canela, M., Clish, C. B., Dennis, C., Salas-Salvado, J., Hruby, A., Liang, L., Toledo, E., Corella, D., Ros, E., Fito, M., Gomez-Gracia, E., Aros, F., Fiol, M., Lapetra, J., Serra-Majem, L., Estruch, R., Martinez-Gonzalez, M. A. Tags: Etiology, Cardiovascular Disease, Diet and Nutrition, Epidemiology, Acute Coronary Syndromes Source Type: research
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