Selective Sphingosine-1-Phosphate Receptor 1 Modulation Attenuates Experimental Intracerebral Hemorrhage [Basic Sciences]

Conclusions—
S1PR1 modulation via RP101075 provides protection in experimental ICH. Together with the advantageous pharmacological features of RP101075, these results warrant further investigations of its mechanisms of action and translational values in ICH patients.

Source: Stroke - June 26, 2016 Category: Neurology Authors: Sun, N., Shen, Y., Han, W., Shi, K., Wood, K., Fu, Y., Hao, J., Liu, Q., Sheth, K. N., Huang, D., Shi, F.-D. Tags: Intracranial Hemorrhage Basic Sciences Source Type: research