0291 : Mitochondrial permeability transition pore opening might contribute to ventricular arrhythmia maintenance

Conclusions Here we suggest that the FK506-induced calcium overload promotes mitochondrial calcium accumulation and leads to mPTP opening. We propose that mPTP opening should be considered as an arrhythmogenic substrate. The author hereby declares no conflict of interest
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research