Cough-Associated Changes in CSF Flow in Chiari I Malformation Evaluated by Real-Time MRI [SPINE]

CONCLUSIONS:
Real-time MR imaging noninvasively showed a transient decrease in CSF flow across the foramen magnum after coughing in symptomatic patients with Chiari I malformation, a phenomenon not seen in healthy participants. Our results provide preliminary evidence that the physiology-based imaging method used here has the potential to be an objective clinical test to differentiate symptomatic from asymptomatic patients with Chiari I malformation.

Source: American Journal of Neuroradiology - May 12, 2016 Category: Radiology Authors: Bhadelia, R. A., Patz, S., Heilman, C., Khatami, D., Kasper, E., Zhao, Y., Madan, N. Tags: SPINE Source Type: research