Incidence and Predictive Factors for Recovery of Ovarian Function in Amenorrheic Women in Their 40s Treated With Letrozole [Rapid Communications]

Conclusion These results emphasize the challenge in determining definitive menopause in women with chemotherapy-induced amenorrhea. The risk of OFR during treatment with AIs in amenorrheic women in their 40s is high, and AI therapy should be avoided in these patients.

http://jco.ascopubs.org/cgi/content/short/34/14/1594?rss=1

Source: Journal of Clinical Oncology - May 2, 2016 Category: Cancer & Oncology Authors: Krekow, Hellerstedt, Collea, Papish, Diggikar, Resta, Vukelja, Holmes, Reddy, Asmar, Wang, Fox, Peck, OShaughnessy Tags: Hormonal Therapy, Rapid Communications Source Type: research