Prolonged PR interval, first-degree heart block and adverse cardiovascular outcomes: a systematic review and meta-analysis

Conclusions Data from observational studies suggests a possible association between prolonged PR interval and significant increases in atrial fibrillation, heart failure and mortality. Future prospective studies are needed to confirm the relationships reported, consider possible mechanisms and define the optimal monitoring strategy for such patients.

http://heart.bmj.com/cgi/content/short/102/9/672?rss=1

Source: Heart - April 11, 2016 Category: Cardiology Authors: Kwok, C. S., Rashid, M., Beynon, R., Barker, D., Patwala, A., Morley-Davies, A., Satchithananda, D., Nolan, J., Myint, P. K., Buchan, I., Loke, Y. K., Mamas, M. A. Tags: Bradyarrhythmias and heart block, Drugs: cardiovascular system, Acute coronary syndromes, Epidemiology Arrhythmias and sudden death Source Type: research