Metabolic dysfunction and adipose tissue macrophages: Is there more to glean from studying the lean?

Metabolic syndrome is a serious health condition that affects approximately 34% of adults. Hallmarks of this syndrome include abdominal obesity, elevated triglyceride levels, reduced HDL cholesterol, hypertension, hyperglycemia, and insulin resistance, and those affected are at heightened risk for the development of Type 2 diabetes, cardiovascular disease, and stroke. Over the past 20 years, an increasing role for low grade, sterile inflammation in insulin resistance and metabolic syndrome has been appreciated.
Source: Translational Research - Category: Research Authors: Tags: Commentary Source Type: research