Metabolic dysfunction and adipose tissue macrophages: Is there more to glean from studying the lean?
Metabolic syndrome is a serious health condition that affects approximately 34% of adults. Hallmarks of this syndrome include abdominal obesity, elevated triglyceride levels, reduced HDL cholesterol, hypertension, hyperglycemia, and insulin resistance, and those affected are at heightened risk for the development of Type 2 diabetes, cardiovascular disease, and stroke. Over the past 20 years, an increasing role for low grade, sterile inflammation in insulin resistance and metabolic syndrome has been appreciated.
Source: Translational Research - Category: Research Authors: David L. Morris, Carmella Evans-Molina Tags: Commentary Source Type: research
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