ATP-binding cassette transporters in reproduction: a new frontier

CONCLUSIONS
The ABC transporters have various roles across multiple reproductive tissues. Knowledge of efflux direction, tissue distribution, substrate specificity and regulation of the ABC transporters in the placenta and other reproductive tissues is rapidly expanding. This will allow better understanding of the disposition of specific substrates within reproductive tissues, and facilitate development of novel treatments for reproductive disorders as well as improved approaches to protecting the developing fetus.

Source: Human Reproduction Update - February 16, 2016 Category: OBGYN Authors: Bloise, E., Ortiga-Carvalho, T. M., Reis, F. M., Lye, S. J., Gibb, W., Matthews, S. G. Tags: Reviews Source Type: research