Clarithromycin and Short-term Risk of Cardiovascular EventsClarithromycin and Short-term Risk of Cardiovascular Events

Clarithromycin is associated with an increased short-term risk of cardiovascular morbidity, especially in older patients and those with hypertension or diabetes, according to a new population-based study. Reuters Health Information
Source: Medscape Infectious Diseases Headlines - Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news

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Authors: Gali B, Eyawo O, Hull MW, Samji H, Zhang W, Sereda P, Lima VD, McGrail K, Montaner JSG, Hogg RS, Moore D, COAST Study Team Abstract Objective: To characterize the incidence of select chronic comorbidities in the era of modern (pre-integrase inhibitor) highly active antiretroviral therapy (HAART) in British Columbia, Canada. Methods: We used data from the Comparative Outcomes And Service Utilization Trends (COAST) study, a population-based cohort study of people living with HIV (PLWH), to determine incidence rates of six key chronic diseases among PLWH receiving HAART in BC from 2000 to 2012. The selected d...
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
Empagliflozin (EMPA), a sodium-glucose cotransporter 2 (SGLT2) inhibitor, was shown to attenuate cardiovascular and renal morbidity in patients with type 2 diabetes in the EMPA-REG Outcome trial. EMPA decreased the risk of incident or worsening nephropathy, progression to macroalbuminuria, and the combined endpoint of doubling of serum creatinine and need for renal replacement therapy. This is due, in part, to a reduction in glomerular hypertension. Mayer and colleagues wondered whether EMPA was still effective in patients taking commonly used background medications that also affect glomerular hemodynamics.
Source: Kidney International - Category: Urology & Nephrology Tags: In This Issue Source Type: research
Conditions:   Healthy Individuals;   Diabetes;   Hypertension;   Fabry Disease;   Metabolic Disease;   Alzheimer Disease;   Dementia;   Limbal Insufficiency;   Phlyctenulosis;   Ocular Rosacea;   Graft Versus Host Disease in Eye;   Dry Eye Syndrome Intervention:   Sponsor:   National Taiwan University Hospital Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 18 July 2019Source: International Review of NeurobiologyAuthor(s): Dafin Fior Muresanu, Aruna Sharma, Ranjana Patnaik, Preeti K. Menon, Herbert Mössler, Hari Shanker SharmaAbstractThere is a growing trend of hypertension among military and civilian populations due to lifetime stressful situations. If hypertension is uncontrolled it leads to development of diabetes and serious neurological complications. Most of the World populations live in temperate zone across the World. Thus, a possibility exists that these hypertensive and diabetic people may have external heat as potential risk ...
Source: International Review of Neurobiology - Category: Neuroscience Source Type: research
Publication date: Available online 17 July 2019Source: Neuroscience LettersAuthor(s): Alagudurai Krishnamoorthy, Murugan Sevanan, Sugumar Mani, Mangayarkarasi Balu, Sravani Balaji, Ramajayan PAbstractParkinson disease occurs due to the depletion of dopaminergic neurons in brain resulting in decreased dopamine level and abnormal protein aggregation. Chrysin is a flavonoid which possesses pharmacological properties against various diseases like hypertension, diabetes, cancer, etc. According to the recent literatures, it is evidenced that chrysin protects mice against Focal Cerebral Ischemia/Reperfusion Injury. The present st...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
If you’ve been diagnosed with kidney stones (urolithiasis), you may have several options for treatment. These include medical therapy, extracorporeal shock wave lithotripsy (ESWL), percutaneous nephrolithotripsy (PCNL), and ureteroscopy. A brief anatomy of the urinary tract The urinary tract includes kidneys (two organs that filter waste and extra water from the blood) ureters (two tubes bringing urine from each kidney to the bladder) bladder (organ that collects urine) urethra (a single tube through which urine in the bladder passes out of the body). The evaluation for kidney stones If your symptoms suggest kidney...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Kidney and urinary tract Men's Health Women's Health Source Type: blogs
 Relationship between the Use of Aluminium Utensils for Cooking Meals and Chronic Aluminum Toxicity in Patients on Maintenance Hemodialysis: A Case Control Study. J Assoc Physicians India. 2019 Apr;67(4):52-56 Authors: Bichu S, Tilve P, Kakde P, Jain P, Khurana S, Ukirade V, Jawandhiya P, Dixit A, Bhasin N, Billa V, Kumar R, Kothari J Abstract Background: Chronic aluminum toxicity (CAT) in end stage kidney disease (ESKD) patients is now a rare clinical disorder, unlike in the past, because of improvements in hemodialysis water purification systems and discontinuation of use of aluminum hydroxide a...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
CONCLUSION: Psychological distress was associated with elevated levels of CRP among South African adults. However, the association was confounded by a range of factors, with demographic variables (age, sex and population group) having the largest confounding effect. These findings indicate that CRP is not a useful biomarker of psychological distress, and that additional work is needed on the underlying psychobiology of psychological distress. PMID: 31307562 [PubMed - as supplied by publisher]
Source: Acta Neuropsychiatrica - Category: Psychiatry Tags: Acta Neuropsychiatr Source Type: research
ConclusionConsidering patients with chronic subdural hematomas our study demonstrated that the significant variables predicting outcome are chronic subdural hematomas occurring secondary to an overdraining ventriculo-peritoneal shunt, a history of seizures, and a low level of consciousness measured by either the Markwalder or the Glasgow Coma Score. Interestingly all of these variables are determined prior to the patient arriving at hospital. Our study highlights the need for early presentation prior to clinical deterioration as the major determinant of outcome.
Source: Interdisciplinary Neurosurgery - Category: Neurosurgery Source Type: research
by Barbara Daly, Konstantinos A. Toulis, Neil Thomas, Krishna Gokhale, James Martin, Jonathan Webber, Deepi Keerthy, Kate Jolly, Ponnusamy Saravanan, Krishnarajah Nirantharakumar
Source: PLoS Medicine - Category: Internal Medicine Authors: Source Type: research
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