Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle
Conclusion
Our data reveal a central role of the innate immune system, namely Toll-like receptor 3, to mediate angiogenesis upon release of cytoplasmic RNAs by mechanotransduction of SWT.
Source: Cardiovascular Research - Category: Cardiology Authors: Holfeld, J., Tepeköylü, C., Reissig, C., Lobenwein, D., Scheller, B., Kirchmair, E., Kozaryn, R., Albrecht-Schgoer, K., Krapf, C., Zins, K., Urbschat, A., Zacharowski, K., Grimm, M., Kirchmair, R., Paulus, P. Tags: Vascular Biology Source Type: research