Enhanced atheroprotection and lesion remodelling by targeting the foam cell and increasing plasma cholesterol acceptors

Conclusion
These studies demonstrate a mutually beneficial relationship between PLIN2 deficiency and elevated apoA-I/HDL-C in preventing atherosclerosis development. The data support that targeting foam cell components to mobilize cholesterol may be a promising strategy to enhance the atheroprotection of plasma cholesterol acceptors.

Source: Cardiovascular Research - January 25, 2016 Category: Cardiology Authors: Son, S.-H., Goo, Y.-H., Choi, M., Saha, P. K., Oka, K., Chan, L. C. B., Paul, A. Tags: Vascular Biology Source Type: research