Perinatal citalopram does not prevent the effect of prenatal stress on anxiety, depressive‐like behaviour and serotonergic transmission in adult rat offspring

Conclusions: Prenatal citalopram does not prevent the behavioural changes or reduction in serotonergic transmission to target areas induced by prenatal stress. It has adverse behavioural effects in the offspring of control rats, which, together with the lack of any change in prenatally‐stressed rats, may be due to inhibition of the foetal 5HT transporter thereby preventing normal development of the 5HT system. This article is protected by copyright. All rights reserved.
Source: European Journal of Neuroscience - Category: Neuroscience Authors: Tags: Research Report Source Type: research