Sex differences in porcine left ventricular myocardial remodeling due to right ventricular pacing

Conclusions Male and female porcine hearts respond differently to RV pacing. Males, most likely due to a higher extracellular matrix turnover, demonstrated a significant LV dilatation, followed by a strong induction of pro-hypertrophic program, and an earlier development of symptomatic HF.
Source: Biology of Sex Differences - Category: Biology Source Type: research