Osteoprotegerin secreted by inflammatory and invasive breast cancer cells induces aneuploidy, cell proliferation and angiogenesis
Conclusions:
These results highlight the role of OPG in reprogramming normal mammary epithelial cells to a tumorigenic state and suggest promising avenues for treating inflammatory breast cancer as well as highly invasive breast cancer with new therapeutic targets.
Source: BMC Cancer - Category: Cancer & Oncology Authors: Sudeshna GoswamiNeelam Sharma-Walia Source Type: research
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