Immunology and Immunotherapy of Hepatocellular Carcinoma

NCI’s Center for Cancer Research (CCR) Grand Rounds Dr. Greten received his medical training at ChristianAlbrechts University in Kiel, Germany. He did an internship in Munich followedby a postdoctoral fellowship at The Johns Hopkins University, Baltimore,Maryland, in the laboratory of Drew Pardoll and Liz Jaffee, where he initiatedhis work in the field of tumor immunology. In 1999 Dr. Greten finished histraining in internal medicine, medical oncology, and gastroenterology atHannover Medical School. He then served as an associate professor in theDepartment of Gastroenterology, Hepatology, and Endocrinology. In February 2010Dr. Greten joined CCR as Head of the Gastrointestinal Malignancy Section, whichis now part of the Thoracic and Gastrointestinal Oncology Branch.Dr. Greten has published more than 70 peer-reviewedpapers on basic tumor immunology, translational research studies inhepatocellular carcinoma (HCC), as well as on clinical trials in differentgastrointestinal malignancies, including HCC. He also lead the Group forHepatobiliary Carcinoma from 2006 until 2010 where he coordinated and directedthe German Clinical Trial Group (AIO). Currently, Dr. Greten is a member of theNCI Gastrointestinal Malignancy Faculty and Immunology Faculty. Dr. Greten's major research interest has been the effectof tumor development and tumor-specific treatment on immune response in cancerpatients. In addition, his group is interested in identification of tumorsuppressor mechanisms with a spe...
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