Neuropilin-2 induced by transforming growth factor-β augments migration of hepatocellular carcinoma cells

Conclusions:
These data suggest that NRP2 associates with a less differentiated, mesenchymal-like HCC phenotype and that NRP2 plays an important role in tumor cell migration upon TGF-β-dependent HCC progression.

Source: BMC Cancer - November 16, 2015 Category: Cancer & Oncology Authors: Philipp WittmannMarkus GrubingerChristian GrögerHeidemarie HuberWolfgang SieghartMarkus Peck-RadosavljevicWolfgang Mikulits Source Type: research