Serial Alberta Stroke Program Early CT Score From Baseline to 24 Hours in Solitaire Flow Restoration With the Intention for Thrombectomy Study: A Novel Surrogate End Point for Revascularization in Acute Stroke [Clinical Sciences]

Conclusions— Twenty-four-hour ASPECTS provides better prognostic information compared with baseline ASPECTS. Predictors of dramatic infarct progression on ASPECTS are hyperglycemia, hypertension, and nonreperfusion. Serial ASPECTS change from baseline to 24 hours predicts clinical outcome, providing an early surrogate end point for thrombectomy trials. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01054560.
Source: Stroke - Category: Neurology Authors: Tags: Cerebrovascular disease/stroke, Brain Circulation and Metabolism, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research