[Radiotherapy for gliomas in adults: What are the stakes of the follow-up?]

[Radiotherapy for gliomas in adults: What are the stakes of the follow-up?]
Cancer Radiother. 2015 Aug 13;
Authors: Atallah V, Gariel F, Gillon P, Crombé A, Mazeron JJ
Abstract
Linked to the difference of prognosis, the terms and conditions of the follow-up of low-grade and high-grade gliomas treated by irradiation differ highly. Patients treated for a low-grade glioma have prolonged survival. In this case, monitoring of toxicities linked to the treatment is a major objective. Opportunistic infections and depression are corticosteroids side effects widely underestimated. Radionecrosis search and differentiation with recurrent disease are done by MRI. Perfusion and spectroscopy showing a choline/creatine ratio increase are in favour of disease recurrence. Cognitive status and quality of life must be evaluated during the follow-up. They have to be evaluated by adapted scales. Cognitive rehabilitation improves interestingly the post-treatment cognitive status. Pseudoprogression rates for high-grade gliomas are near 20%. MRI is the benchmark imaging for its diagnosis. Diffusion weight imaging and spectroscopy are actually the most interesting techniques.
PMID: 26278986 [PubMed - as supplied by publisher]

Source: Cancer Radiotherapie - August 13, 2015 Category: Cancer & Oncology Authors: Atallah V, Gariel F, Gillon P, Crombé A, Mazeron JJ Tags: Cancer Radiother Source Type: research