Research on garlic capsule and selenium – Vitamin A, Vitamin C, Vitamin E applied in therapy of acute hepatocellular damage in a rat model

Conclusion Collectively, the results suggest that therapeutic dose of LIS elicits toxicity in male rats through induction of oxidative damage and depletion of cellular adenosine triphosphate (ATP). The reversal effects of GAR and SACE during LIS treatment suggest that these antioxidants may find clinical application in cellular damage involving reactive oxygen species (ROS) and ATP.
Source: Journal of Acute Disease - Category: Emergency Medicine Source Type: research

Related Links:

High blood pressure: A common diagnosis, that shows hardly any symptoms, but can be deadly. Hardened arteries and blood forced too hard against artery walls can lead to a heart attack or stroke. Fortunately, there are lifestyle improvements that can lower blood pressure and potentially save your life.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Conclusion: There was a high prevalence of MetS and abnormal ECG among the studied population. Abnormal ECG findings were more common in men with no differential association in people with or without MetS. However, a significant association existed between certain components of MetS and ECG abnormalities in men only. Male gender and HDLc were independent predictors of ECG Abnormalities.Keyword: Electrocardiography, metabolic syndrome, africans.
Source: African Health Sciences - Category: African Health Source Type: research
Background: The 2017 ACC/AHA Guideline categorized blood pressure into 4 levels:normal (SBP
Source: African Health Sciences - Category: African Health Source Type: research
Introduction: Hypertension is a cause and consequence of chronic kidney disease globally. The other factors that work in concert with hypertension to cause CKD are yet to be clearly elucidated. Studies have identified proteinuria, dyslipidemia, obesity, smoking and family history of CKD as renal risk factors. Due to the high morbidity and mortality associated with occurrence of CKD including the enormous financial burden involved in its management, the knowledge of prevention and understanding of the risk factors for development of CKD is highly essential. Therefore, Identifying well defined risk factors that display stron...
Source: African Health Sciences - Category: African Health Source Type: research
Background: Maternal factors are determinants of birth outcome which includes birth weight, haematological indices and mode of delivery of their babies.Objectives: To determine the impact of parity and gestational age of hypertensive mothers on some neonatal variables.Methods: A hospital based cross-sectional study of measurement of neonatal variables (birth weight, red blood cells and mode of delivery) among hypertensive mothers and their controls was conducted over a period of six months. Data were analyzed using the Statistical Package for Social Sciences program (SPSS), version 20.Results: There were statistically sign...
Source: African Health Sciences - Category: African Health Source Type: research
Background: Non-communicable diseases (NCD) are of international public health concern. Of more concern are people living with HIV (PLHIV), who have the increased risk of developing NCDs, such as hypertension, stroke and diabetes. Research has revealed that there is a relationship between knowledge of NCD risk factors and risk perceptions in the general population. Therefore, an assessment of PLHIV ’s NCD risk factors knowledge is quite critical, to design effective NCD prevention programmes.Objective: To assess the level of knowledge of modifiable risk factors for NCDs and its associated factors among adults living ...
Source: African Health Sciences - Category: African Health Source Type: research
Recurrent stroke is becoming an increasingly important public health issue owing to the increased risk of disability and death. However, population-based studies investigating the rate of recurrent stroke in China are rare. We explored the rate and determinants of recurrent stroke within 1 and 5 years after the initial stroke in a rural population in China. Data for stroke events were obtained from the Tianjin Brain Study, conducted between 1992 and 2016. The age-standardized rates of recurrent stroke within the first year and the first 5 years after the initial stroke were calculated for this period. Determinants of recur...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
AbstractThe presence of hypertensive mediated organ damage is related to increased vascular risk and mortality and its prevention should be a therapeutic target and a surrogate marker of in/adequate blood pressure control. In old adult hypertensive patients the therapeutic target should be to prevent major cardiovascular events, but in young hypertensive subjects the focus should be pointed on preventing the development of hypertensive mediated organ damage, since most of the hard events are preceded by functional and structural tissues injury. Hypertension Guidelines of the European Society of Cardiology and European Soci...
Source: High Blood Pressure and Cardiovascular Prevention - Category: Cardiology Source Type: research
Publication date: Available online 22 January 2020Source: Genes &DiseasesAuthor(s): Sergei N. Orlov, Artem M. Tverskoi, Svetlana V. Sidorenko, Larisa V. Smolyaninova, Olga D. Lopina, Nickolai O. Dulin, Elizaveta A. KlimanovaAbstractWith an exception of few reports, the plasma concentration of ouabain and marinobufagenin, mostly studied cardiotonic steroids (CTS) assessed by immunoassay techniques, is less than 1 nM. During the last 3 decades, the implication of these endogenous CTS in the pathogenesis of hypertension and other volume-expanded disorders is widely disputed. The threshold for inhibition by CTS of human an...
Source: Genes and Diseases - Category: Genetics & Stem Cells Source Type: research
Publication date: Available online 21 January 2020Source: Genes &DiseasesAuthor(s): W.E.I. Zilun, Y.A.N.G. Yining, L.I. Qiaoling, Y.I.N. Yong, W.E.I. Zhonghai, Z.H.A.N.G. Wenfeng, M.U. Dan, N.I. Jie, S.U.N. Xuan, X.U. BiaoAbstract and KeywordsHypertension (HT) is the most common public-health challenge and shows a high incidence around the world. Cardiovascular diseases are the leading cause of mortality and morbidity among the elderly (age> 65 years) in the United States. Now, there is widespread acceptance of the causal link between HT and acute myocardial infarction (MI). This is the first data-mining study to id...
Source: Genes and Diseases - Category: Genetics & Stem Cells Source Type: research
More News: Cardiology | Cardiovascular | Emergency Medicine | Garlic | Heart | Hypertension | Lisinopril | Liver | Selenium | Study | Toxicology | Urology & Nephrology | Vitamins