Abstract 3368: Sustained adrenergic signaling activates pro-inflammatory prostaglandin network in ovarian carcinoma

Conclusion Increased adrenergic stimulation results in a pro-inflammatory milieu mediated by prostaglandins that drives tumor progression and metastasis in ovarian cancer.Citation Format: Archana S. Nagaraja, Piotr Dorniak, Nouara Sadaoui, Guillermo Armaiz-Pena, Behrouz Zand, Sherry Y. Wu, Julie K. Allen, Rajesha Rupaimoole, Cristian Rodriguez-Aguayo, Sunila Pradeep, Lin Tan, Rebecca A. Previs, Jean M. Hansen, Peiying Yang, Garbiel Lopez-Berestein, Susan K. Lutgendorf, Steve Cole, Anil K. Sood. Sustained adrenergic signaling activates pro-inflammatory prostaglandin network in ovarian carcinoma. [abstract]. In: Proceedings of the 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18-22; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Res 2015;75(15 Suppl):Abstract nr 3368. doi:10.1158/1538-7445.AM2015-3368

Source: Cancer Research - August 2, 2015 Category: Cancer & Oncology Authors: Nagaraja, A. S., Dorniak, P., Sadaoui, N., Armaiz-Pena, G., Zand, B., Wu, S. Y., Allen, J. K., Rupaimoole, R., Rodriguez-Aguayo, C., Pradeep, S., Tan, L., Previs, R. A., Hansen, J. M., Yang, P., Lopez-Berestein, G., Lutgendorf, S. K., Cole, S., Sood, A. K Tags: Tumor Biology Source Type: research