A phase 1 clinical trial of sequential pralatrexate followed by a 48‐hour infusion of 5‐fluorouracil given every other week in adult patients with solid tumors

CONCLUSIONSThe recommended dose of PDX was 148 mg/m2. A subset of heavily pretreated patients had PFS durations of ≥6 months with this regimen. Cancer 2015. © 2015 American Cancer Society.

Source: Cancer - August 4, 2015 Category: Cancer & Oncology Authors: Jean L. Grem, Mary E. Kos, Ruby E. Evande, Jane L. Meza, James K. Schwarz Tags: Original Article Source Type: research