Disposition Kinetics of Cathinone and its Metabolites after Oral Administration in Rats

CONCLUSION: This study revealed a dynamic interplay between cathinone disposition kinetics and its impact on organ-specific metabolic profiles in rats. These results have significant implications for drug development, pharmacovigilance, and clinical practices involving cathinone. Investigating the correlation between the changes in biomarkers found in the brain and the levels of cathinone and cathine is essential for informed decision- making in medical practices and further research into the pharmacological properties of cathinone.PMID:38752643 | DOI:10.2174/0113892002300638240513065512

Source: Current Drug Metabolism - May 16, 2024 Category: Drugs & Pharmacology Authors: Fahad Y Sabei Ibrahim Khardali Mohamed A Al-Kasim Emad Sayed Shaheen Magbool Oraiby Ahmad Alamir Banji David Saeed Alshahrani Abdulmajeed M Jali Mohammed Attafi Mohammed Y Albeishy Ibraheem Attafi Source Type: research