Dereplication tools for Rhizophora mangle extracts from different mangrove areas and their potential against Staphylococcus aureus
This study aimed to investigate the chemical profile of Rhizophora mangle leaves from fringe, basin, and transition mangrove zones and their bactericidal/bacteriostatic potential against S. aureus. R. mangle leaves were collected monthly in 2018 from litterfall in three different zones of the mangrove of Guaratiba State Reserve: fringe, basin, and transition. Extracts were prepared from the material collected in October and December for LC-HRMS/MS analysis, and dereplication was performed using a molecular library search and the classical molecular networking GNPS platform. The minimum inhibitory concentrations (MICs) of the aqueous extract of R. mangle against S. aureus were determined. No S. aureus growth was observed compared to the control for extracts collected from September to December. Different compounds were annotated in each region, yet a marked presence of phenolic compounds was noted, among them glycosylated flavonoid derivatives of quercetin and kaempferol. The results suggest bactericidal/bacteriostatic activity for extracts of R. mangle leaves collected in 2018 from three mangrove forest zones.PMID:38702295 | DOI:10.1002/cbdv.202400687
Source: Chemistry and Biodiversity - Category: Biochemistry Authors: Amanda Let ícia da Silva Pontes Carla Monteiro Leal Manuela Pereira Lucas Gabriela Caama ño Muiño da Silva Jo ão Vitor Braga Alves Peixoto Juliana Barbosa Succar Vinicius Ribeiro Flores Ida Carolina Neves Direito Antonio Jorge Ribeiro da Silva Filipe Source Type: research
More News: Biochemistry | Chemistry | Databases & Libraries | Flavonoids | Molecular Biology | Staphylococcus Aureus | Study