Functional implications of NHR-210 enrichment in C. elegans cephalic sheath glia: insights into metabolic and mitochondrial disruptions in Parkinson's disease models

In conclusion, the deficiency of the nuclear hormone receptor nhr-210 in alpha-synuclein expressing strain of C. elegans, results in altered mitochondrial function, coupled with alterations in vital metabolite levels. These findings underline the functional and physiological importance of nhr-210 enrichment in CEPsh glia.PMID:38691171 | DOI:10.1007/s00018-024-05179-2

Source: Cell Research - May 1, 2024 Category: Cytology Authors: Rohil Hameed Anam Naseer Ankit Saxena Mahmood Akbar Pranoy Toppo Arunabh Sarkar Sanjeev K Shukla Aamir Nazir Source Type: research