DIREN mitigates DSS-induced colitis in mice and attenuates collagen deposition via inhibiting the Wnt/ β-catenin and focal adhesion pathways
CONCLUSION: DIREN exerts a protective effect against DSS-induced UC by ameliorating colonic fibrosis via regulation of focal adhesion and the WNT/β-catenin signaling pathway, thereby inhibiting fibroblast migration and reducing collagen secretion.PMID:38678963 | DOI:10.1016/j.biopha.2024.116671
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - Category: Drugs & Pharmacology Authors: Weizhi Lai Yingying Wang Chen Huang Hao Xu Xunjie Zheng Ke Li Jue Wang Zhaohuan Lou Source Type: research
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