Identification and functional analysis of the hub Ferroptosis-Related gene EZH2 in diabetic kidney disease

CONCLUSION: Overall, our data shouwed that histone H3K27 methyltransferase EZH2 could regulate the renal tubular epithelial cell ferroptosis by suppressing SLC7A11 in DKD, which may serve as a credible reliable indicator for diagnosing DKD and a potential target for treatment.PMID:38678670 | DOI:10.1016/j.intimp.2024.112138

Source: International Immunopharmacology - April 28, 2024 Category: Allergy & Immunology Authors: Han Wang Jiajia Wang Qingsen Ran Yan Leng Tiejun Liu Zhuang Xiong Dixin Zou Weipeng Yang Source Type: research