Neonatal herpes: case series in two obstetric centres over a 10-year period (2013-2023), France

Conclusion: This case series confirms that neonates at risk for HSV disease and poor outcome are those born to HSV-seronegative mothers, preterm infants, and those who received acyclovir after onset of symptoms (mainly because mothers did not present evidence of acute HSV infection). Our study confirms the major role of HSV-1 and the frequency of its early post-natal acquisition. What is known: • Neonatal herpes simplex virus infection is rare but motality and morbidity rates are high after disseminted disease and encephalitis. National recommendations exist worldwide but mangement of this disease is not always easy. What is new: • As in France epidemiology of neonatal herpes is poorly described, our report is potentially an important addition to the existing literature. Moreover, we describe local practice that may be useful to physicians.PMID:38678161 | DOI:10.1007/s00431-024-05581-9

Source: Herpes - April 27, 2024 Category: Infectious Diseases Authors: Elise Bouthry Vincent Portet-Sulla Melek Manai Bouokazi Claire P érillaud-Dubois Fran çois-Charles Javaugue Laure Jule Claire Boithias Nolwenn Le Sach é Mostafa Mokhtari Diane Carri ère Louise Sonnier Rafik Benammar Alexandra Letourneau Alexandre J Vi Source Type: research