Effects of a Global < em > Rab27a < /em > Null Mutation on Murine PVAT and Cardiovascular Function

CONCLUSIONS: Global RAB27A loss impacted perivascular adipose tissue and thoracic aorta proteomic signatures, altered vasocontractile responses, and decreased left ventricular ejection fraction in mice.PMID:38660803 | DOI:10.1161/ATVBAHA.124.320969

Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 25, 2024 Category: Cardiology Authors: Ashley Soucy Christian Potts Abigail Kaija Anne Harrington Marissa McGilvrey George L Sutphin Ron Korstanje Benjamin Tero Jacob Seeker Ilka Pinz Calvin Vary Larisa Ryzhova Lucy Liaw Source Type: research