Non-Detection of HCMV Total Genomic DNA in Human Glioma Cells Genome

CONCLUSION: We found that the genomic DNA of all the samples was negative for HCMV genomic DNA. Thus, HCMV could not be detected in human glioma tumors and we put forward that HCMV genomic DNA was not incorporated into the genomic DNA of glioma cells. Thus, total viral DNA is not involved in the pathogenesis of glioma; however, small viral particles or specific genes might be incorporated into the genomic DNA of glioma cells, leading to cancer development. This prompts further studies for verification.PMID:38650560 | DOI:10.5137/1019-5149.JTN.42717-22.1
Source: Turkish Neurosurgery - Category: Neurosurgery Authors: Source Type: research