miR-29b-3p regulates cardiomyocytes pyroptosis in CVB3-induced myocarditis through targeting DNMT3A

CONCLUSIONS: Our results demonstrate a correlation between the expression of DNMT3A and CVB3-induced pyroptosis in cardiomyocytes. These findings unveil a previously unidentified mechanism by which CVB3 induces cardiac injury through the regulation of miR-29b-3p/DNMT3A-mediated pyroptosis.PMID:38643118 | PMC:PMC11031889 | DOI:10.1186/s11658-024-00576-8

Source: Cellular and Molecular Biology Letters - April 20, 2024 Category: Biochemistry Authors: Ya Wang Zhengyang Zhang Hui Li Min Wang Yuting Qiu Lili Lu Source Type: research