Recurrent Chagas' disease meningomyelitis in an HIV-infected patient

We report a 59-year-old man native from the Northeast region of Brazil, with a second episode of subacute chagasic meningomyelitis. He had long-term multidrug-resistant HIV and had abandoned combined antiretroviral therapy (CD4+ lymphocyte count, 16 cells/mm³, and HIV viral load 169 403 copies/mL). He initially received benznidazole but switched to nifurtimox after developing myelotoxicity. He was discharged home having made a partial neurological improvement. Chagas' disease should be included in the differential diagnosis of meningomyelitis in people living with HIV/AIDS who are from endemic areas of this parasitic disease.PMID:38653547 | DOI:10.1136/pn-2024-004088

Source: Practical Neurology - April 23, 2024 Category: Neurology Authors: Igor Melo de Almeida Aline Borges Moreira da Rocha Jos é Angelo Lauletta Lindoso Vera L úcia Teixeira de Freitas Augusto Cp Oliveira Jose E Vidal Source Type: research