Circ_0000277 promotes the malignant progression of oesophageal squamous cell carcinoma through miR-1294-dependent regulation of DVL3

ConclusionCirc_0000277 promoted ESCC malignant progression through the miR-1294/DVL3 pathway.HighlightsCirc_0000277 expression was upregulated in ESCC tissues and cells.Circ_0000277 contributed to ESCC cell proliferation, migration and invasion.Circ_0000277 induced DVL3 expression through sponging miR-1294.
Source: Molecular and Cellular Toxicology - Category: Cytology Source Type: research