Tumor necrosis factor receptor-associated factor 5 protects against intimal hyperplasia by regulation of macrophage polarization via directly targeting PPAR γ

ConclusionsCollectively, this evidence reveals an important role of TRAF5 in the development of intimal hyperplasia through the regulation of macrophage polarization, which provides a promising target for arterial restenosis-related disease management.

http://link.springer.com/10.1007/s00011-024-01875-8

Source: Inflammation Research - April 20, 2024 Category: Research Source Type: research