Upregulation of Nrf2 signaling: A key molecular mechanism of Baicalin's neuroprotective action against diabetes-induced cognitive impairment
CONCLUSIONS AND IMPLICATIONS: Bai demonstrates a great therapeutic potential for attenuating DCI. The antioxidant defense and anti-inflammatory actions of Bai were mediated through the KEAP1-Nrf2 axis. These findings advance our understanding of potential treatment approaches for DCI, a common complication associated with diabetes.PMID:38631145 | DOI:10.1016/j.biopha.2024.116579
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - Category: Drugs & Pharmacology Authors: Yanfang Zheng Chenxiang Wang Wenjing Liu Jiaying Chen Yibin Sun Dennis Chang Huan Wang Wen Xu Jin-Jian Lu Xian Zhou Mingqing Huang Source Type: research
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