Co-delivery of fucoxanthin and Twist siRNA using hydroxyethyl starch-cholesterol self-assembled polymer nanoparticles for triple-negative breast cancer synergistic therapy

CONCLUSION: Systematic studies revealed that this dual-functional nanomedicine that targets both tumor cells and tumor microenvironment significantly alleviates TNBC orthotopic tumor burden and inhibits lung metastasis, establishing a new paradigm for TNBC therapy.PMID:38636588 | DOI:10.1016/j.jare.2024.04.017

Source: Cell Research - April 18, 2024 Category: Cytology Authors: Zeliang Wu Yuxiang Tang Yuanhui Liu Zhaozhao Chen Yuao Feng Hang Hu Hui Liu Gang Chen Youming Lu Yu Hu Rong Xu Source Type: research