Blocking Pannexin 1 Channels Alleviates Peripheral Inflammatory Pain but not Paclitaxel-Induced Neuropathy

CONCLUSION: Our findings suggest that Panx1 is critical for developing peripheral inflammatory pain and acute nociception involving transient receptor potential vanilloid subtype 1 (TRPV1) but is not essential for neuropathic pain chronicity.PMID:38538230 | DOI:10.31083/j.jin2303064

Source: Journal of Integrative Neuroscience - March 27, 2024 Category: Neuroscience Authors: Julia Borges Paes Lemes Kaue Franco Malange Nathalia Santos Carvalho Amanda Ferreira Neves Marcia Urban-Maldonado Paula Regina Gelinski Kempe Catarine Massucato Nishijima Cecilia Costa Fagundes Celina Monteiro da Cruz Lotufo Sylvia Ottile Suadicani Carlos Source Type: research