Photodynamic anticancer activity evaluation of novel 5-aminolevulinic acid and 3-hydroxypyridinone conjugates

In conclusion, cellular phototoxicity showed a strong correlation with intracellular PpIX fluorescence levels, indicating the potential application of ALA-HPO conjugates in ALA-PDT.PMID:38626642 | DOI:10.1016/j.bmc.2024.117726

Source: Bioorganic and Medicinal Chemistry - April 16, 2024 Category: Chemistry Authors: Jingqi Zhang Shengli Yuan Miaoliang Fan Keren Wang Jianan Guo Anjie Zang Jinhui Ren Weike Su Changjun Zhang Yuanyuan Xie Source Type: research