Isoquercitrin activates the AMP¿activated protein kinase (AMPK) signal pathway in rat H4IIE cells

Conclusions:
Isoquercitrin appears to regulate AMPK activation, thereby enhancing AdipoR1 expression, suppressing SREBP-1 and FAS expressions, and resulting in the regulation of lipid accumulation. These results suggest that isoquercitrin is a novel dietary compound that can be potentially be used to prevent lipid metabolic disorder and nonalcoholic fatty liver disease.

Source: BMC Complementary and Alternative Medicine - February 3, 2014 Category: Complementary Medicine Authors: Jingxin ZhouHisae YoshitomiTonghua LiuBoxin ZhouWen SunLingling QinXiangyu GuoLiansha HuangLili WuMing Gao Source Type: research