A Comparative Analysis on the Potential Anticancer Properties of Tetrahydrocannabinol, Cannabidiol, and Tetrahydrocannabivarin Compounds Through In Silico Approach

CONCLUSION: Overall, in silico predictions of the three cannabinoid compounds revealed that they are good candidates for oral drug formulation. Among the three cannabinoids, THCV is an excellent anticancer aspirant for future chemotherapy with the most favorable results in drug-likeness and ADMET analysis, pharmacological properties evaluation, and cytotoxicity assessment results. Further study on bioevaluation of compounds is needed to elucidate their potential pharmacological activities.PMID:38546067 | DOI:10.31557/APJCP.2024.25.3.839

Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Angelica A Gallardo Mikaela Rose Gutierrez Lyka Alexandrea J Gomez Patricia Arielle O Delos Reyes Sophia Allison A Dones Maria Mikaela U Dumbrique Heather Eena Lim Maria Isabel H Liquido Mary Margaret L Macawile Ella Denese Anne B Maglaqui Angelica Mae G Source Type: research