Does Blocking the Renin-Angiotensin System Mitigate Acute Kidney Injury After Heart Transplantation?

OVER THE past decades, advancements in immunosuppressive therapy, organ preservation, surgical techniques, and postoperative care have led to improved long-term survival after heart transplantation.1,2 Despite these advances, acute kidney injury (AKI) after cardiac transplantation remains a common complication associated with increased morbidity and mortality.3 Heart transplant recipients are at an increased risk of AKI because of pre-existing chronic kidney disease (CKD), often attributed to prolonged low cardiac output state or cardiorenal syndrome.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Editorial Source Type: research