Efficacy of combinational treatment versus nicotinamide monotherapy in the prevention of ultraviolet radiation-induced skin cancer

CONCLUSION: NAM-PG was as effective in delaying UVR-induced tumour onset as NAM-mono. The reduction in 6-4PP lesions may indicate that the mechanism of NAM-PG is better suited for photoprotection than NAM-mono. NAM-mono was superior to NAM-Met, indicating a dose-dependency of NAM's photoprotection. These results highlight a potential for combining photoprotective compounds to enhance photoprotection.PMID:38599196 | DOI:10.1159/000538445

Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Celina Pihl Flemming Andersen Peter Bjerring Merete Haedersdal Catharina Margrethe Lerche Source Type: research