Comparable outcomes of allogeneic peripheral blood versus bone marrow hematopoietic stem cell transplantation from a sibling donor for pediatric patients

In this study, we showed no significant differences in EFS, OS, TRM, and GVHD, except for acute GVHD grades II–IV, between BMT and PBSCT from sibling donors, using ATG (a total of 7.5 mg/kg). Therefore, PB collection, which is less invasive for donors and less labor-intensive for doctors, could also be considered an acceptable SC sour ce for sibling donor HSCT in children.
Source: Annals of Hematology - Category: Hematology Source Type: research