20-year depressive symptoms, dementia, and structural neuropathology in older women

DISCUSSION: There are heterogeneous profiles of depressive symptoms and dementia risk. Common neuropathological factors may contribute to both depression and dementia. Highlights The progression of depressive symptoms and concurrent dementia risk is heterogeneous. Emerging depressive symptoms may be a prodromal symptom of dementia. Cerebrovascular disease and AD are potentially shared neuropathological factors.PMID:38591250 | DOI:10.1002/alz.13781

Source: The Journal of Alzheimers Association - April 9, 2024 Category: Psychiatry Authors: Andrew J Petkus Xinhui Wang Diana Younan Lauren E Salminen Susan M Resnick Stephen R Rapp Mark A Espeland Margaret Gatz Keith F Widaman Ramon Casanova Helena Chui Ryan T Barnard Sarah A Gaussoin Joseph S Goveas Kathleen M Hayden Victor W Henderson Bonnie Source Type: research