Depressive Symptoms and Plasma Markers of Alzheimer's Disease and Neurodegeneration: A Coordinated Meta-Analysis of 8 Cohort Studies

CONCLUSIONS: Late-life depressive symptoms did not show an association to plasma biomarkers of AD pathology. However, in APOE ε4 allele carriers, a more profound role of neurodegeneration was suggested with depressive symptoms.PMID:38553327 | DOI:10.1016/j.jagp.2024.03.004

Source: The American Journal of Geriatric Psychiatry - March 29, 2024 Category: Psychiatry Authors: Emma L Twait Maria Kamarioti Inge M W Verberk Charlotte E Teunissen Astrid C J Nooyens W M Monique Verschuren Pieter Jelle Visser Martijn Huisman Almar A L Kok P Eline Slagboom Marian Beekman Dina Vojinovic Nico Lakenberg M Arfan Ikram Isabel K Schuurmans Source Type: research