The mmu_circ_003062, hsa_circ_0075663/miR-490-3p/CACNA1H axis mediates apoptosis in renal tubular cells in association with endoplasmic reticulum stress following ischemic acute kidney injury

CONCLUSION: The involvement of mmu_circ_003062, hsa_circ_0075663/miR-490-3p/CACNA1H/GRP78 and CHOP axis is significant in the development of ischemic AKI. Moreover, hsa_circ_0075663 has potential as an early diagnostic biomarker.PMID:38554447 | DOI:10.1016/j.intimp.2024.111956

Source: International Immunopharmacology - March 30, 2024 Category: Allergy & Immunology Authors: Qiang Zheng Xiaozhou Li Xuan Xu Xianming Tang Bacha Hammad Jihong Xing Dongshan Zhang Source Type: research