Effects of PCV10 and PCV13 on pneumococcal serotype 6C disease, carriage, and antimicrobial resistance

CONCLUSIONS: In contrast to PCV10, PCV13 vaccination consistently protected against 6C IPD and NPC in children, and provided some level of indirect protection to adults, supporting that serotype 6A but not 6B provides cross-protection to 6C. Vaccine policy makers and regulators should consider the effects of serotype 6A-containing PCVs against serotype 6C disease in their decisions.PMID:38553292 | DOI:10.1016/j.vaccine.2024.03.065

Source: Vaccine - March 29, 2024 Category: Allergy & Immunology Authors: Lindsay R Grant Germaine Hanquet Ingrid T Sep úlveda-Pachón Christian Theilacker Marc Baay Mary P E Slack Luis Jodar Bradford D Gessner Source Type: research