Evaluation of tumor response to immune checkpoint inhibitors by a 3D immunotumoroid model

ConclusionOur immunotumoroid model replicated the multicellular nature of the tumor microenvironment sufficiently for preclinical ICI screening. This model could enable valuable insights into the complex interactions between cancer cells, the immune system, and the microenvironment. This is a feasibility study on a small number of cases, and additional studies with larger case numbers are required including correlation with clinical response.
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research