Abdominal normothermic regional perfusion in the United States: current state and future directions

Curr Opin Organ Transplant. 2024 Mar 21. doi: 10.1097/MOT.0000000000001144. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Normothermic regional perfusion (NRP) is a novel procurement technique for donation after circulatory death (DCD) in the United States. It was pioneered by cardiothoracic surgery programs and is now being applied to abdominal-only organ donors by abdominal transplant programs.RECENT FINDINGS: Liver and kidney transplantation from thoracoabdominal NRP (TA-NRP) donors in the United States was found to have lower rates of delayed kidney graft function and similar graft and patient survival versus recipients of cardiac super rapid recovery (SRR) DCD donors. The excellent outcomes with NRP have prompted the expansion of NRP technology to abdominal transplant programs.SUMMARY: Excellent early outcomes with liver and kidney transplantation have prompted the growth of NC-NRP procurement for abdominal-only DCD donors across the US, and now requires standardization of technical and nontechnical aspects of this procedure.PMID:38506730 | DOI:10.1097/MOT.0000000000001144
Source: Current Opinion in Organ Transplantation - Category: Transplant Surgery Authors: Source Type: research