Cancers, Vol. 16, Pages 1291: Perioperative Chemotherapy for Gastro-Esophageal or Gastric Cancer: Anthracyclin Triplets versus FLOT

Conclusion(s): Real-world data showed no significant OS improvement for FLOT-treated patients compared to anthracyclin triplets, despite more staging laparoscopies. However, FLOT patients demonstrated higher rates of neoadjuvant therapy completion, proceeding to adjuvant therapy, and increased pCR rates. Therefore, we recommend the continued use of neoadjuvant FLOT therapy in the current clinical setting.

Source: Cancers - March 26, 2024 Category: Cancer & Oncology Authors: Julie F. M. Geerts Charl ène J. van der Zijden Pieter C. van der Sluis Manon C. W. Spaander Grard A. P. Nieuwenhuijzen Camiel Rosman Hanneke W. M. van Laarhoven Rob H. A. Verhoeven Bas P. L. Wijnhoven Sjoerd M. Lagarde Bianca Mostert Tags: Article Source Type: research