Clinical Accuracy of Serum Neurofilament Light to Differentiate Frontotemporal Dementia from Primary Psychiatric Disorders is Age-Dependent

Frontotemporal dementia (FTD) is one of the most common forms of early-onset dementia (1). The most common presentation is the behavioural variant of FTD (bvFTD) manifesting in personality and behavioural changes (2). Symptoms like decreased empathy and emotional reactivity, apathy, and compulsive behaviours significantly overlap with those of non-neurodegenerative primary psychiatric disorders (PPD) including major depressive disorder (MDD), bipolar disorder (BD), schizophrenia (SZ), and personality disorders (2,3).

Source: The American Journal of Geriatric Psychiatry - March 22, 2024 Category: Geriatrics Authors: Victoria Light, Sherri Lee Jones, Elham Rahme, Katerine Rousseau, Sterre de Boer, Lisa Vermunt, Mahdie Soltaninejad, Charlotte Teunissen, Yolande Pijnenburg, Simon Ducharme, For Signature Consortium Tags: Regular Research Article Source Type: research